26-Cholesterol Hydroxylase in Rat Corpora Lutea: A Negative Regulator of Progesterone Secretion1

In vitro synthesis of progesterone by swine corpora lutea.

Comparison of induced corpora lutea from prepuberal gilts and spontaneous corpora lutea from mature gilts: in vitro progesterone production.

Prepuberal (P) gilts were induced to ovulate with pregnant mare serum gonadotropin followed 72 h later by human chorionic gonadotropin (hCG). Three P gilts and three mature (M) gilts each were ovariectomized on d 10, 14, 18, 22 and 26 (d 0 = day of hCG for P gilts and onset of estrus for M gilts). Gilts ovariectomized on d 14, 18, 22 and 26 were hysterectomized on d 6 to ensure maintenance of t...

Lipid metabolism in regressing rat corpora lutea of pregnancy.

Lipid accumulation is a hallmark of corpus luteum regression and we characterized lipids stored in rat corpora lutea of pregnancy between days 21 and 24 post coitum, the period of luteolysis. A 10-fold rise in lutein triglyceride concentrations occurred between days 21 and 24, which represented the major alteration in luteal lipid metabolism during luteolysis, coinciding with the appearance of ...

Effect of number of corpora lutea and fetuses on concentrations of progesterone in blood of goats.

The objectives of this study were to assess relationships between 1) number of corpora lutea (CL) and concentrations of progesterone (P) in plasma of goats from onset of estrus (d 0) to d 45 of pregnancy and 2) concentration of P and number of fetuses on d 45. Blood from 79 pregnant goats was obtained on d 0 and 1 and at 48-h intervals thereafter to d 25 of gestation. Additional samples were co...

Effects of corpora lutea removal and replacement with progesterone on pregnancy in goats.

p ROGESTERONE is predominantly a hormone of pregnancy and is required for (a) the growth and secretion of the glands in the uterine mucosa preparatory to implantation of the ovum (b) the nutrition and protection of the embryo during the time when it is lying free in the uterus (c) the development of the placenta and membranes after implantation (d) lobule-alveolar mammary growth (e) maintenance...